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	<title>
	Comments on: New Zealand&#8217;s Stone Weta &#8211; Genuine Cryogenics	</title>
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	<link>https://www.heatherhastie.com/mountain-stone-weta/</link>
	<description>My take on our world</description>
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		<title>
		By: Heather Hastie		</title>
		<link>https://www.heatherhastie.com/mountain-stone-weta/#comment-15788</link>

		<dc:creator><![CDATA[Heather Hastie]]></dc:creator>
		<pubDate>Mon, 19 Jun 2017 00:01:23 +0000</pubDate>
		<guid isPermaLink="false">https://www.heatherhastie.com/?p=4321#comment-15788</guid>

					<description><![CDATA[In reply to &lt;a href=&quot;https://www.heatherhastie.com/mountain-stone-weta/#comment-15787&quot;&gt;GravelInspectorAidan&lt;/a&gt;.

Thanks for the explanation about how it would work in humans - that&#039;s interesting! And it makes it clear why it&#039;s unlikely to happen for us.]]></description>
			<content:encoded><![CDATA[<p>In reply to <a href="https://www.heatherhastie.com/mountain-stone-weta/#comment-15787">GravelInspectorAidan</a>.</p>
<p>Thanks for the explanation about how it would work in humans &#8211; that&#8217;s interesting! And it makes it clear why it&#8217;s unlikely to happen for us.</p>
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		<title>
		By: GravelInspectorAidan		</title>
		<link>https://www.heatherhastie.com/mountain-stone-weta/#comment-15787</link>

		<dc:creator><![CDATA[GravelInspectorAidan]]></dc:creator>
		<pubDate>Sun, 18 Jun 2017 23:57:01 +0000</pubDate>
		<guid isPermaLink="false">https://www.heatherhastie.com/?p=4321#comment-15787</guid>

					<description><![CDATA[&quot;Up to 100mMolar proline solution&quot; at one point ; with a molar mass of 115.13 g·mol^(−1) that would be about 11 grams of proline per litre of cell fluids. Or for an average human to get to similar concentrations, you&#039;d need to get something like 750g of this chemical uniformly distributed through body cells. Then get it out again when you thaw your &quot;corpsicle&quot;.
Most of the SF stories that use &quot;suspended animation&quot; as a plot element do make some sort of nod to this sort of issue by having the revived crew wake up in a pretty manky condition, and have lots of plumbing in the &quot;hibernaculum&quot; ; you can see why.

Personally, I suspect that there isn&#039;t a way to achieve useful &quot;suspended animation&quot; without a significant risk of death and/ or mutilation for the suspendee. Small molecules are, of necessity, relatively simple, and there are not that many of them compared to larger molecules (which have more atoms, so can be more complex). But larger molecules have correspondingly lower molalities when in solution at the 10g/kg dose that we&#039;re talking about here, so you have to get more cryoprotective bang per gram of the molecule. This significantly reduces the credible search volume in possible chemicals, and leads to my deduction that there probably isn&#039;t a molecule that works well enough to become a medical procedure administered by a robot with an acceptably low death rate. 
File under &quot;unobtanium&quot; along with the FTL drive and diving through wormholes. If humans are ever going to tan their skins under a star that isn&#039;t the Sun, they&#039;ll get there in a generation ship, and probably at under 0.1 of The Speed Limit.

(Some people have pet rats, but I have a pet rant. Or several.)]]></description>
			<content:encoded><![CDATA[<p>&#8220;Up to 100mMolar proline solution&#8221; at one point ; with a molar mass of 115.13 g·mol^(−1) that would be about 11 grams of proline per litre of cell fluids. Or for an average human to get to similar concentrations, you&#8217;d need to get something like 750g of this chemical uniformly distributed through body cells. Then get it out again when you thaw your &#8220;corpsicle&#8221;.<br />
Most of the SF stories that use &#8220;suspended animation&#8221; as a plot element do make some sort of nod to this sort of issue by having the revived crew wake up in a pretty manky condition, and have lots of plumbing in the &#8220;hibernaculum&#8221; ; you can see why.</p>
<p>Personally, I suspect that there isn&#8217;t a way to achieve useful &#8220;suspended animation&#8221; without a significant risk of death and/ or mutilation for the suspendee. Small molecules are, of necessity, relatively simple, and there are not that many of them compared to larger molecules (which have more atoms, so can be more complex). But larger molecules have correspondingly lower molalities when in solution at the 10g/kg dose that we&#8217;re talking about here, so you have to get more cryoprotective bang per gram of the molecule. This significantly reduces the credible search volume in possible chemicals, and leads to my deduction that there probably isn&#8217;t a molecule that works well enough to become a medical procedure administered by a robot with an acceptably low death rate.<br />
File under &#8220;unobtanium&#8221; along with the FTL drive and diving through wormholes. If humans are ever going to tan their skins under a star that isn&#8217;t the Sun, they&#8217;ll get there in a generation ship, and probably at under 0.1 of The Speed Limit.</p>
<p>(Some people have pet rats, but I have a pet rant. Or several.)</p>
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		<item>
		<title>
		By: Ann German		</title>
		<link>https://www.heatherhastie.com/mountain-stone-weta/#comment-15786</link>

		<dc:creator><![CDATA[Ann German]]></dc:creator>
		<pubDate>Sun, 18 Jun 2017 23:38:05 +0000</pubDate>
		<guid isPermaLink="false">https://www.heatherhastie.com/?p=4321#comment-15786</guid>

					<description><![CDATA[Excellent - thanks!]]></description>
			<content:encoded><![CDATA[<p>Excellent &#8211; thanks!</p>
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		<title>
		By: Trevor		</title>
		<link>https://www.heatherhastie.com/mountain-stone-weta/#comment-15775</link>

		<dc:creator><![CDATA[Trevor]]></dc:creator>
		<pubDate>Sun, 18 Jun 2017 08:46:31 +0000</pubDate>
		<guid isPermaLink="false">https://www.heatherhastie.com/?p=4321#comment-15775</guid>

					<description><![CDATA[Seasonal metabolic changes mean that species like this are particularly susceptible to the effects of climate change :-(]]></description>
			<content:encoded><![CDATA[<p>Seasonal metabolic changes mean that species like this are particularly susceptible to the effects of climate change 🙁</p>
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		<title>
		By: Lee Knuth		</title>
		<link>https://www.heatherhastie.com/mountain-stone-weta/#comment-15769</link>

		<dc:creator><![CDATA[Lee Knuth]]></dc:creator>
		<pubDate>Sat, 17 Jun 2017 16:18:22 +0000</pubDate>
		<guid isPermaLink="false">https://www.heatherhastie.com/?p=4321#comment-15769</guid>

					<description><![CDATA[Thanks for the share.  What a marvelous creature.]]></description>
			<content:encoded><![CDATA[<p>Thanks for the share.  What a marvelous creature.</p>
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		<title>
		By: Ken		</title>
		<link>https://www.heatherhastie.com/mountain-stone-weta/#comment-15765</link>

		<dc:creator><![CDATA[Ken]]></dc:creator>
		<pubDate>Sat, 17 Jun 2017 02:09:34 +0000</pubDate>
		<guid isPermaLink="false">https://www.heatherhastie.com/?p=4321#comment-15765</guid>

					<description><![CDATA[What a cool kiwi!]]></description>
			<content:encoded><![CDATA[<p>What a cool kiwi!</p>
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